Chasing the unknown primary.

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Cancer of unknown primary

Cancer of unknown primary (CUP) ranges within top 10 cancers in both incidence and mortality. As primary identification is crucial to choosing treatment, guidelines on CUP emphasize the diagnostic strategy. Whether guidelines are complied with, or if they are indeed helpful, is however unclear. We compared procedures performed in suspected CUP patients with recommendations of national guideline...

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Most patients with cancer present with an obvious primary site of their disease, but in a few no primary is apparent even after investigation. These patients have always presented clinical challenges. How far should investigations be taken if a fatal outcome is likely and the tests are unpleasant? What treatments should be used? Recent advances in oncology have made the management of these pati...

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Cancer of unknown primary site.

Copyright © 2014 Massachusetts Medical Society Cancer of unknown primary site is a heterogeneous group of cancers for which the anatomical site of origin remains occult after detailed investigations.1,2 The emergence of sophisticated imaging, immunohistochemical testing, and molecular-profiling tools has influenced our approach to unknown primary cancer, although it has also increased the ambig...

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Management of unknown primary tumor.

A 37-year-old man is initially seen with a 4-month history of a gradually enlarging, painless rightsided neck mass. He denies any otalgia, dysphagia, odynophagia, hoarseness, fever, night sweats, or weight loss. His medical history is significant only for mild COPD, and he has smoked two packs per day for 20 years. He is married and is a right-handed police officer. Examination of the head and ...

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ژورنال

عنوان ژورنال: BMJ

سال: 1980

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.281.6254.1566-a